منابع مشابه
Angiotensin II receptor blockers.
BUMC PROCEEDINGS 2003;16:123–126 The angiotensin II receptor blockers (ARBs) represent a newer class of antihypertensive agents. Their mechanism of action differs from that of the angiotensin-converting enzyme (ACE) inhibitors, which also affect the renin-angiotensin system. The ARBs were developed to overcome several of the deficiencies of ACE inhibitors: competitive inhibition of ACE results ...
متن کاملAngiotensin II type 1 receptor blockers.
In the 1970s, a series of observations demonstrated that angiotensin II has deleterious effects on the heart and kidney and that patients with high levels of plasma renin activity are at a higher risk of developing stroke or myocardial infarction than those with low plasma renin activity.1,2 Thereafter, the development of pharmacological probes that block the renin-angiotensin system helped def...
متن کاملAngiotensin II receptor blockers and nephropathy trials.
This is the first of a series of reports on the American Diabetes Association (ADA) 61st Scientific Sessions held in Philadelphia in June 2001. It covers topics related to angiotensin II receptor blockers (ARBs) and nephropathy. At a symposium at the 61st Scientific Sessions of the ADA in June 2001, the results of three recent diabetic nephropathy trials with angiotensin II subtype 1 receptor a...
متن کاملAngiotensin II receptor blockers: current perspective.
and molecular biology techniques have revealed another aspect of Ang II as a tissue hormone or autocoid with paracrine, autocrine and intracrine actions.4,5 The renal renin and circulating components of RAS are produced in amounts greater by several orders of magnitude than the amounts produced by extra-renal tissues and are mainly or solely responsible for the systemic hormonal and hemodynamic...
متن کاملAngiotensin Ii Receptor Blockers: an Overview
Blockage of the renin-angiotensin system (RAS) is now recognized as an effective approach to the treatment of hypertension and congestive heart failure. Today, it is possible to antagonize the effects of angiotensin II (AT-II) more specifically by blocking its receptors by using nonpeptide receptor antagonists. AT-II-receptor antagonists were developed as agents that would more completely block...
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ژورنال
عنوان ژورنال: Baylor University Medical Center Proceedings
سال: 2003
ISSN: 0899-8280,1525-3252
DOI: 10.1080/08998280.2003.11927893